目的研究铁皮石斛对运动训练大鼠物质代谢及抗运动疲劳能力的影响。方法以大强度耐力训练大鼠为模型，55只42d龄雄性Wistar大鼠为对象，随机分为5组:静止对照组(C组)、运动对照组(T组)、运动ig低剂量铁皮石斛组(TML组)，运动ig中剂量铁皮石斛组(TMM组)，运动ig高剂量铁皮石斛组(TMH组)，每组10只(剔除不符合实验要求的大鼠)。采用专业灌胃器每天ig一次，低、中、高剂量组ig剂量分别为1。5、3、4。5g·kg^-1·d^-1，ig体积为5mL·kg^-1，C、T组ig等量生理盐水。末次训练24h后，测定体重、力竭游泳时间及血红蛋白等生化指标。结果TM各组间体重无显著差异，且大于T组(P<；0。05)，小于C组(P<；0。05)；TM各组力竭游泳时间长于C、T组(P<；0。01)，且随剂量增大而延长；长时间力竭运动导致肝糖原、肌糖原储量下降；血尿素氮上升；血红蛋白下降。结论补充铁皮石斛可以促进蛋白质合成，抑制氨基酸和蛋白质分解，提高血红蛋白含量和糖原的储备，增强抗疲劳能力，具有多靶点、多途径的显著特点。

OBJECTIVE To study the effects of Dendrobium officinale Kimura et Migo on the rats substance metabolism and anti-exercise fatigue capacity in the exercise training. METHODS High-intensity endurance training rat was as a model. Divided the 6-week-old male(42 d age)Wistar rats 55 into 5 groups of 10(removed the rats, which are not meeting the requirement): still group(group C) ,exercise group(group T),exercise ig low-dose Dendrobium officinale Kimura et Migo group of(group TML), exercise ig middle-dose of Dendrobium officinale Kimura et Migo group(group TMM), exercise ig high-dose of Dendrobium officinale Kimura et Migo group (group TMH). Gavage using professional device ig once a day, group TML, Group TMM, group TMH ig dose was 1.5、3、4.5 g· kg^-1·d^-1, the ig volume 5 mL·kg^-1, Group C and group T were added to ig the same amount of saline. For 24 h after the last training, measured weight, exhaustive swimming time, Hemoglobin and other biochemical markers. RESULTS The TM each weight no significant differences, and greater than the group T(P<0.05) less than group C(P<0.05). TM swimming time is longer than the group C and group T(P<0.01), and the dose increased and extended. Prolonged exhaustive exercise lead to liver glycogen、muscle glycogen reserves decreased(group T(P<0.01), groups TM(P<0.05) lower than in group C. TM each group of liver glycogen higher than the group T, no significant differences between each group of the TM, with the dose increase and higher).In addition, blood urea nitrogen rise. Hemoglobin decreased .CONCLUSION Dendrobium officinale Kimura et Migo supplement can promote protein synthesis, inhibition of amino acid and protein degradation, thereby increasing the hemoglobin content and glycogen reserves, enhanced resistance to fatigue, it has a multi-target, multi-channel features.